A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism
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Author / Creator
Pradas-Juni, Marta , Hansmeier, Nils R. , Link, Jenny C. , Schmidt, Elena , Larsen, Bjørk Ditlev , Klemm, Paul , Meola, Nicola , Topel, Hande , Loureiro, Rute , Dhaouadi, Ines , Kiefer, Christoph A. , Schwarzer, Robin , Khani, Sajjad , Oliverio, Matteo , Awazawa, Motoharu , Frommolt, Peter , Heeren, Joerg , Scheja, Ludger , Heine, Markus , Dieterich, Christoph , Büning, Hildegard , Yang, Ling , Cao, Haiming , Jesus, Dario F. De , Kulkarni, Rohit N. , Zevnik, Branko , Tröder, Simon E. , Knippschild, Uwe , Edwards, Peter A. , Lee, Richard G. , Yamamoto, Masayuki , Ulitsky, Igor , Fernandez-Rebollo, Eduardo , Vallim, Thomas Q. de Aguiar and Kornfeld, Jan-Wilhelm
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in metabolism. Here we show that a high fraction of lncRNAs, but not protein-coding mRNAs, are repressed during diet-induced obesity (DIO) and refeeding, whilst nutrient deprivation induced lncRNAs in mouse...
Alternative Titles
Full title
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism
Authors, Artists and Contributors
Author / Creator
Hansmeier, Nils R.
Link, Jenny C.
Schmidt, Elena
Larsen, Bjørk Ditlev
Klemm, Paul
Meola, Nicola
Topel, Hande
Loureiro, Rute
Dhaouadi, Ines
Kiefer, Christoph A.
Schwarzer, Robin
Khani, Sajjad
Oliverio, Matteo
Awazawa, Motoharu
Frommolt, Peter
Heeren, Joerg
Scheja, Ludger
Heine, Markus
Dieterich, Christoph
Büning, Hildegard
Yang, Ling
Cao, Haiming
Jesus, Dario F. De
Kulkarni, Rohit N.
Zevnik, Branko
Tröder, Simon E.
Knippschild, Uwe
Edwards, Peter A.
Lee, Richard G.
Yamamoto, Masayuki
Ulitsky, Igor
Fernandez-Rebollo, Eduardo
Vallim, Thomas Q. de Aguiar
Kornfeld, Jan-Wilhelm
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4ccddec6eb3c494894508ff7177b7683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4ccddec6eb3c494894508ff7177b7683
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14323-y