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A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4ccddec6eb3c494894508ff7177b7683

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in metabolism. Here we show that a high fraction of lncRNAs, but not protein-coding mRNAs, are repressed during diet-induced obesity (DIO) and refeeding, whilst nutrient deprivation induced lncRNAs in mouse...

Alternative Titles

Full title

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4ccddec6eb3c494894508ff7177b7683

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4ccddec6eb3c494894508ff7177b7683

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-14323-y

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