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Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells...

Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4cd8c0380e154f7c80aed36a986a3c6f

Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells for structural studies

About this item

Full title

Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells for structural studies

Publisher

United States: PeerJ, Inc

Journal title

PeerJ (San Francisco, CA), 2018-08, Vol.6, p.e5449-e5449, Article e5449

Language

English

Formats

Publication information

Publisher

United States: PeerJ, Inc

More information

Scope and Contents

Contents

Diacylglycerol kinases (DGKs) are lipid kinases that modulate the levels of lipid second messengers, diacylglycerol and phosphatidic acid. Recently, increasing attention has been paid to its α isozyme (DGKα) as a potential target for cancer immunotherapy. DGKα consists of the N-terminal regulatory domains including EF-hand motifs and C1 domains, an...

Alternative Titles

Full title

Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells for structural studies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4cd8c0380e154f7c80aed36a986a3c6f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4cd8c0380e154f7c80aed36a986a3c6f

Other Identifiers

ISSN

2167-8359

E-ISSN

2167-8359

DOI

10.7717/peerj.5449

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