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Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogene...

Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogene...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d1be1828419469cb3c5255b08aa5e9a

Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta

About this item

Full title

Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-12, Vol.12 (1), p.7199-7199, Article 7199

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Type I collagen (Col1) is the most abundant protein in mammals. Col1 contributes to 90% of the total organic component of bone matrix. However, the precise cellular origin and functional contribution of Col1 in embryogenesis and bone formation remain unknown. Single-cell RNA-sequencing analysis identifies Fap
+
cells and Fsp1
+
cells as...

Alternative Titles

Full title

Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4d1be1828419469cb3c5255b08aa5e9a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d1be1828419469cb3c5255b08aa5e9a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-27563-3

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