Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension
About this item
Full title
Author / Creator
Di Pietro, Paola , Carrizzo, Albino , Sommella, Eduardo , Oliveti, Marco , Iacoviello, Licia , Di Castelnuovo, Augusto , Acernese, Fausto , Damato, Antonio , De Lucia, Massimiliano , Merciai, Fabrizio , Iesu, Paola , Venturini, Eleonora , Izzo, Raffaele , Trimarco, Valentina , Ciccarelli, Michele , Giugliano, Giuseppe , Carnevale, Roberto , Cammisotto, Vittoria , Migliarino, Serena , Virtuoso, Nicola , Strianese, Andrea , Izzo, Viviana , Campiglia, Pietro , Ciaglia, Elena , Levkau, Bodo , Puca, Annibale A and Vecchione, Carmine
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Sortilin has been positively correlated with vascular disorders in humans. No study has yet evaluated the possible direct effect of sortilin on vascular function. We used pharmacological and genetic approaches coupled with study of murine and human samples to unravel the mechanisms recruited by sortilin in the vascular system. Sortilin induced endo...
Alternative Titles
Full title
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension
Authors, Artists and Contributors
Author / Creator
Carrizzo, Albino
Sommella, Eduardo
Oliveti, Marco
Iacoviello, Licia
Di Castelnuovo, Augusto
Acernese, Fausto
Damato, Antonio
De Lucia, Massimiliano
Merciai, Fabrizio
Iesu, Paola
Venturini, Eleonora
Izzo, Raffaele
Trimarco, Valentina
Ciccarelli, Michele
Giugliano, Giuseppe
Carnevale, Roberto
Cammisotto, Vittoria
Migliarino, Serena
Virtuoso, Nicola
Strianese, Andrea
Izzo, Viviana
Campiglia, Pietro
Ciaglia, Elena
Levkau, Bodo
Puca, Annibale A
Vecchione, Carmine
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4ecf605ecd9844b59930a9c8987dcc75
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4ecf605ecd9844b59930a9c8987dcc75
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI146343
