A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease pati...
A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background With the emergence of microglia-modulating therapies there is an urgent need for reliable biomarkers to evaluate microglial activation states. Methods Using mouse models and human induced pluripotent stem cell-derived microglia (hiMGL), genetically modified to yield the most opposite homeostatic (TREM2-knockout) and disease-associated (G...
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A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls
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TN_cdi_doaj_primary_oai_doaj_org_article_4f94573c7b924aa89443dd73131fdc40
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f94573c7b924aa89443dd73131fdc40
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-023-00657-w
