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CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fbfd858eb664ea8891c7763c979d634

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

About this item

Full title

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-05, Vol.8 (1), p.15464-10, Article 15464

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Although CRISPR/Cas9 genome editing has provided numerous opportunities to interrogate the functional significance of any given genomic site, there is a paucity of data on the extent of molecular scars inflicted on the mouse genome. Here we interrogate the molecular consequences of CRISPR/Cas9-mediated deletions at 17 sites in four loci of the mous...

Alternative Titles

Full title

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4fbfd858eb664ea8891c7763c979d634

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fbfd858eb664ea8891c7763c979d634

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms15464

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