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Structural determinants of nuclear export signal orientation in binding to exportin CRM1

Structural determinants of nuclear export signal orientation in binding to exportin CRM1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50e3f5cb3a1f4f2187bd39729518a95e

Structural determinants of nuclear export signal orientation in binding to exportin CRM1

About this item

Full title

Structural determinants of nuclear export signal orientation in binding to exportin CRM1

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2015-09, Vol.4

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

The Chromosome Region of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recognition of their nuclear export signals (NESs), which are highly variable in sequence and structure. The plasticity of the CRM1-NES interaction is not well understood, as there are many NES sequences that seem incompatible with structur...

Alternative Titles

Full title

Structural determinants of nuclear export signal orientation in binding to exportin CRM1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_50e3f5cb3a1f4f2187bd39729518a95e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50e3f5cb3a1f4f2187bd39729518a95e

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.10034

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