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FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer...

FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50f8f3c833674dccaaf12b8c6d633226

FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis

About this item

Full title

FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis

Publisher

England: BioMed Central

Journal title

Cell communication and signaling, 2021-01, Vol.19 (1), p.3-3, Article 3

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that is overexpressed or activated in several advanced-stage solid cancers. It is known to play both kinase-dependent and -independent roles in promoting tumor progression and metastasis. Numerous inhibitors, targeting either the enzymatic or scaffolding activities of FAK have been gener...

Alternative Titles

Full title

FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_50f8f3c833674dccaaf12b8c6d633226

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50f8f3c833674dccaaf12b8c6d633226

Other Identifiers

ISSN

1478-811X

E-ISSN

1478-811X

DOI

10.1186/s12964-020-00671-1

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