FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer...
FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Contents
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that is overexpressed or activated in several advanced-stage solid cancers. It is known to play both kinase-dependent and -independent roles in promoting tumor progression and metastasis. Numerous inhibitors, targeting either the enzymatic or scaffolding activities of FAK have been gener...
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FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis
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TN_cdi_doaj_primary_oai_doaj_org_article_50f8f3c833674dccaaf12b8c6d633226
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50f8f3c833674dccaaf12b8c6d633226
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-020-00671-1