SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins
SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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SPACA6 is a sperm-expressed surface protein that is critical for gamete fusion during mammalian sexual reproduction. Despite this fundamental role, little is known about how SPACA6 specifically functions. We elucidated the crystal structure of the SPACA6 ectodomain at 2.2-Å resolution, revealing a two-domain protein containing a four-helix bundle a...
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SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_5103ed85da4846eba054e5b2109b21e5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5103ed85da4846eba054e5b2109b21e5
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03883-y
