Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasi...
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aging and mechanical overload are prominent risk factors for osteoarthritis (OA), which lead to an imbalance in redox homeostasis. The resulting state of oxidative stress drives the pathological transition of chondrocytes during OA development. However, the specific molecular pathways involved in disrupting chondrocyte redox homeostasis remain uncl...
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Full title
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis
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TN_cdi_doaj_primary_oai_doaj_org_article_517ac253fd8341f3a065917ccf49ce58
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_517ac253fd8341f3a065917ccf49ce58
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28385-7
