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ArticlesPeer ReviewedFull Text
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis
Author / Creator:Kang, Donghyun ; Lee, Jeeyeon ; Jung, Jisu ; Carlson, Bradley A. ; Chang, Moon Jong ; Chang, Chong Bum ; Kang, Seung-Baik ; Lee, Byung Cheon ; Gladyshev, Vadim N. ; Hatfield, Dolph L. ; Lee, Byeong Jae ; Kim, Jin-Hong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.779-779, Article 779
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Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes
Author / Creator:Mariotti, Marco ; Ridge, Perry G. ; Zhang, Yan ; Lobanov, Alexei V. ; Pringle, Thomas H. ; Guigo, Roderic ; Hatfield, Dolph L. ; Gladyshev, Vadim N.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e33066
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ArticlesPeer ReviewedFull Text
Hydrogen Peroxide Probes Directed to Different Cellular Compartments
Author / Creator:Malinouski, Mikalai ; Zhou, You ; Belousov, Vsevolod V. ; Hatfield, Dolph L. ; Gladyshev, Vadim N.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-01, Vol.6 (1), p.e14564
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Both Maximal Expression of Selenoproteins and Selenoprotein Deficiency Can Promote Development of Type 2 Diabetes-Like Phenotype in Mice
Author / Creator:Labunskyy, Vyacheslav M. ; Lee, Byung Cheon ; Handy, Diane E. ; Loscalzo, Joseph ; Hatfield, Dolph L. ; Gladyshev, Vadim N.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Antioxidants & redox signaling, 2011-06, Vol.14 (12), p.2327-2336
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Structure–Function Relations, Physiological Roles, and Evolution of Mammalian ER-Resident Selenoproteins
Author / Creator:Shchedrina, Valentina A. ; Zhang, Yan ; Labunskyy, Vyacheslav M. ; Hatfield, Dolph L. ; Gladyshev, Vadim N.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Antioxidants & redox signaling, 2010-04, Vol.12 (7), p.839-849
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Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine
Author / Creator:Turanov, Anton A. ; Everley, Robert A. ; Hybsier, Sandra ; Renko, Kostja ; Schomburg, Lutz ; Gygi, Steven P. ; Hatfield, Dolph L. ; Gladyshev, Vadim N.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0140353-e0140353
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Reduced reliance on the trace element selenium during evolution of mammals
Author / Creator:Lobanov, Alexey V ; Hatfield, Dolph L ; Gladyshev, Vadim N
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2008-03, Vol.9 (3), p.R62-1924, Article R62
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Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity
Author / Creator:Canter, Jessica A. ; Ernst, Sarah E. ; Peters, Kristin M. ; Carlson, Bradley A. ; Thielman, Noelle R. J. ; Grysczyk, Lara ; Udofe, Precious ; Yu, Yunkai ; Cao, Liang ; Davis, Cindy D. ; Gladyshev, Vadim N. ; Hatfield, Dolph L. ; Tsuji, Petra A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-09, Vol.22 (19), p.10651
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The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways
Author / Creator:Tsuji, Petra A. ; Carlson, Bradley A. ; Yoo, Min-Hyuk ; Naranjo-Suarez, Salvador ; Xu, Xue-Ming ; He, Yiwen ; Asaki, Esther ; Seifried, Harold E. ; Reinhold, William C. ; Davis, Cindy D. ; Gladyshev, Vadim N. ; Hatfield, Dolph L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-04, Vol.10 (4), p.e0124487
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ArticlesPeer ReviewedFull Text
Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes
Author / Creator:Xu, Xue-Ming ; Carlson, Bradley A ; Mix, Heiko ; Zhang, Yan ; Saira, Kazima ; Glass, Richard S ; Berry, Marla J ; Gladyshev, Vadim N ; Hatfield, Dolph L
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2007-01, Vol.5 (1), p.e4-e4
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ArticlesPeer ReviewedFull Text
Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease
Author / Creator:Yoo, Min-Hyuk ; Gu, Xinglong ; Xu, Xue-Ming ; Kim, Jin-Young ; Carlson, Bradley A. ; Patterson, Andrew D. ; Cai, Huaibin ; Gladyshev, Vadim N. ; Hatfield, Dolph L.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Antioxidants & redox signaling, 2010-04, Vol.12 (7), p.819-827
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ArticlesPeer ReviewedFull Text
Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication
Author / Creator:Yoo, Min-Hyuk ; Xu, Xue-Ming ; Carlson, Bradley A. ; Patterson, Andrew D. ; Gladyshev, Vadim N. ; Hatfield, Dolph L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2007-10, Vol.2 (10), p.e1112-e1112
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ArticlesPeer ReviewedFull Text
Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice
Author / Creator:Tsuji, Petra A. ; Carlson, Bradley A. ; Naranjo-Suarez, Salvador ; Yoo, Min-Hyuk ; Xu, Xue-Ming ; Fomenko, Dmitri E. ; Gladyshev, Vadim N. ; Hatfield, Dolph L. ; Davis, Cindy D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-12, Vol.7 (12), p.e50574
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ArticlesPeer ReviewedFull Text
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery
Author / Creator:Xu, Xue-Ming ; Turanov, Anton A. ; Carlson, Bradley A. ; Yoo, Min-Hyuk ; Everley, Robert A. ; Nandakumar, Renu ; Sorokina, Irina ; Gygi, Steven P. ; Gladyshev, Vadim N. ; Hatfield, Dolph L. ; Valentine, Joan Selverstone
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21430-21434
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ArticlesPeer ReviewedFull Text
Selenoproteins Are Essential for Proper Keratinocyte Function and Skin Development
Author / Creator:Sengupta, Aniruddha ; Lichti, Ulrike F. ; Carlson, Bradley A. ; Ryscavage, Andrew O. ; Gladyshev, Vadim N. ; Yuspa, Stuart H. ; Hatfield, Dolph L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-08, Vol.5 (8), p.e12249
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Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)
Author / Creator:Mahdi, Yassin ; Xu, Xue-Ming ; Carlson, Bradley A. ; Fradejas, Noelia ; Günter, Paul ; Braun, Doreen ; Southon, Eileen ; Tessarollo, Lino ; Hatfield, Dolph L. ; Schweizer, Ulrich
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0127349-e0127349
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Osteo-Chondroprogenitor–Specific Deletion of the Selenocysteine tRNA Gene, Trsp, Leads to Chondronecrosis and Abnormal Skeletal Development: A Putative Model for Kashin-Beck Disease
Author / Creator:Downey, Charlene M. ; Horton, Chelsea R. ; Carlson, Bradley A. ; Parsons, Trish E. ; Hatfield, Dolph L. ; Hallgrímsson, Benedikt ; Jirik, Frank R.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2009-08, Vol.5 (8), p.e1000616
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Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon
Author / Creator:Turanov, Anton A ; Lobanov, Alexey V ; Fomenko, Dmitri E ; Morrison, Hilary G ; Sogin, Mitchell L ; Klobutcher, Lawrence A ; Hatfield, Dolph L ; Gladyshev, Vadim N
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-01, Vol.323 (5911), p.259-261
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ArticlesPeer ReviewedFull Text
Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-α-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus
Author / Creator:Yoo, Min-Hyuk ; Carlson, Bradley A. ; Gladyshev, Vadim N. ; Hatfield, Dolph L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e71427-e71427
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ArticlesPeer ReviewedFull Text
HIF-Independent Regulation of Thioredoxin Reductase 1 Contributes to the High Levels of Reactive Oxygen Species Induced by Hypoxia
Author / Creator:Naranjo-Suarez, Salvador ; Carlson, Bradley A. ; Tsuji, Petra A. ; Yoo, Min-Hyuk ; Gladyshev, Vadim N. ; Hatfield, Dolph L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e30470
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Showing 1 to 20 of 69 results

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Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

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Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes

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Hydrogen Peroxide Probes Directed to Different Cellular Compartments

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Both Maximal Expression of Selenoproteins and Selenoprotein Deficiency Can Promote Development of Type 2 Diabetes-Like Phenotype in Mice

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Structure–Function Relations, Physiological Roles, and Evolution of Mammalian ER-Resident Selenoproteins

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Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine

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Reduced reliance on the trace element selenium during evolution of mammals

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Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity

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The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways

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Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes

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Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease

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Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication

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Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice

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Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

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Selenoproteins Are Essential for Proper Keratinocyte Function and Skin Development

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Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)

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Osteo-Chondroprogenitor–Specific Deletion of the Selenocysteine tRNA Gene, Trsp, Leads to Chondronecrosis and Abnormal Skeletal Development: A Putative Model for Kashin-Beck Disease

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Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon

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Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-α-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus

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HIF-Independent Regulation of Thioredoxin Reductase 1 Contributes to the High Levels of Reactive Oxygen Species Induced by Hypoxia

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