Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
About this item
Full title
Author / Creator
Bian, Yangyang , Zheng, Runsheng , Bayer, Florian P. , Wong, Cassandra , Chang, Yun-Chien , Meng, Chen , Zolg, Daniel P. , Reinecke, Maria , Zecha, Jana , Wiechmann, Svenja , Heinzlmeir, Stephanie , Scherr, Johannes , Hemmer, Bernhard , Baynham, Mike , Gingras, Anne-Claude , Boychenko, Oleksandr and Kuster, Bernhard
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Nano-flow liquid chromatography tandem mass spectrometry (nano-flow LC–MS/MS) is the mainstay in proteome research because of its excellent sensitivity but often comes at the expense of robustness. Here we show that micro-flow LC–MS/MS using a 1 × 150 mm column shows excellent reproducibility of chromatographic retention time (<0.3% coefficient of...
Alternative Titles
Full title
Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_51978dfc79c64bbfbbf6af243fbb23c2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_51978dfc79c64bbfbbf6af243fbb23c2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13973-x
