The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE ε4 Non-carriers
The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE ε4 Non-carriers
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
An ancestral inversion of 900 kb on chromosome 17q21, which includes the microtubule-associated protein tau (
) gene, defines two haplotype clades in Caucasians (H1 and H2). The H1 haplotype has been linked inconsistently with AD. In a previous study, we showed that an SNP tagging this haplotype (rs1800547) was associated with AD risk in a large...
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The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE ε4 Non-carriers
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TN_cdi_doaj_primary_oai_doaj_org_article_51f7b68952d8409faea3d6b0e7f85c0d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_51f7b68952d8409faea3d6b0e7f85c0d
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2019.00327
