Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increas...
Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Targeting the blood-brain barrier (BBB) is a key step for effective brain delivery of nanocarriers. We have previously discovered that combinations of BBB nutrient transporter ligands alanine and glutathione (A-GSH), increase the permeability of vesicular and polypeptide nanocarriers containing model cargo across the BBB. Our aim was to investigate...
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Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model
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TN_cdi_doaj_primary_oai_doaj_org_article_523645badf3a447186bcb29bed3fe0ec
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_523645badf3a447186bcb29bed3fe0ec
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ISSN
2045-8118
E-ISSN
2045-8118
DOI
10.1186/s12987-025-00623-2