Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation reject...
Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection
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Publisher
New Zealand: Taylor & Francis Ltd
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Language
English
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New Zealand: Taylor & Francis Ltd
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Mycophenolate mofetil (MMF), a prodrug of mycophenolic acid (MPA), is an inhibitor of inosine monophosphate dehydrogenase (IMPDH). It preferentially inhibits denovo pathway of guanosine nucleotide synthesis in T and B-lymphocytes and prevents their proliferation, thereby suppresses both cell mediated and humoral immune responses. Clinical trials in...
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Full title
Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection
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TN_cdi_doaj_primary_oai_doaj_org_article_5261e0d1b67e46e0810104568c94c648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5261e0d1b67e46e0810104568c94c648
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ISSN
1176-6336,1178-203X
E-ISSN
1178-203X
DOI
10.2147/tcrm.s3068
