Identification of a specific APOE transcript and functional elements associated with Alzheimer's dis...
Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease
About this item
Full title
Author / Creator
Chen, Qiang , Aguirre, Luis , Liang, Guoming , Zhao, Huanhuan , Dong, Tao , Borrego, Felix , de Rojas, Itziar , Hu, Qichan , Reyes, Christopher , Su, Ling-Yan , Zhang, Bao , Lechleiter, James D , Göring, Harald H H , De Jager, Philip L , Kleinman, Joel E , Hyde, Thomas M , Li, Pan P , Ruiz, Agustín , Weinberger, Daniel R , Seshadri, Sudha and Ma, Liang
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The APOE gene is the strongest genetic risk factor for late-onset Alzheimer's Disease (LOAD). However, the gene regulatory mechanisms at this locus remain incompletely characterized.
To identify novel AD-linked functional elements within the APOE locus, we integrated SNP variants with multi-omics data from human postmortem brains including 2,179...
Alternative Titles
Full title
Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Aguirre, Luis
Liang, Guoming
Zhao, Huanhuan
Dong, Tao
Borrego, Felix
de Rojas, Itziar
Hu, Qichan
Reyes, Christopher
Su, Ling-Yan
Zhang, Bao
Lechleiter, James D
Göring, Harald H H
De Jager, Philip L
Kleinman, Joel E
Hyde, Thomas M
Li, Pan P
Ruiz, Agustín
Weinberger, Daniel R
Seshadri, Sudha
Ma, Liang
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5374844758ed40dc95d178d7f3ae89ee
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5374844758ed40dc95d178d7f3ae89ee
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-024-00751-7
