A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells
A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells
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Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Presenilin (PS)/γ-secretase plays a pivotal role in essential cellular events via proteolytic processing of transmembrane proteins that include APP and Notch receptors. However, how PS/γ-secretase activity is spatiotemporally regulated by other molecular and cellular factors and how the changes in PS/γ-secretase activity influence signaling pathway...
Alternative Titles
Full title
A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_53b08fde53de4967a8b63021b3383a3e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_53b08fde53de4967a8b63021b3383a3e
Other Identifiers
ISSN
1424-8220
E-ISSN
1424-8220
DOI
10.3390/s20215980
