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TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeri...

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_541294edad334aa0b53e65fbfb2bc59b

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

About this item

Full title

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-04, Vol.9 (1), p.1548-14, Article 1548

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs’ functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the first 20q-TERRA knockout models and to demonstrate that TERRAs are essential for telomere length maint...

Alternative Titles

Full title

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_541294edad334aa0b53e65fbfb2bc59b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_541294edad334aa0b53e65fbfb2bc59b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-03916-3

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