SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial...
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Hyperinflammation, hypercoagulation and endothelial injury are major findings in acute and post-COVID-19. The SARS-CoV-2 S protein has been detected as an isolated element in human tissues reservoirs and is the main product of mRNA COVID-19 vaccines. We investigated whether the S protein alone triggers pro-inflammatory and pro-coagulant responses i...
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Full title
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells
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TN_cdi_doaj_primary_oai_doaj_org_article_54152302980441779e88fa1362abf46e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54152302980441779e88fa1362abf46e
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-023-01397-6
