STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism
STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mitophagy is the selective autophagic targeting and removal of dysfunctional mitochondria. While PINK1/Parkin-dependent mitophagy is well-characterized, PINK1/Parkin-independent route is poorly understood. Using structure illumination microscopy (SR-SIM), we demonstrate that the SNARE protein Syntaxin 17 (STX17) initiates mitophagy upon depletion o...
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STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism
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TN_cdi_doaj_primary_oai_doaj_org_article_541fac42676e41b1a63f6626d9812ae1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_541fac42676e41b1a63f6626d9812ae1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10096-1
