Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles
Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles
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Public Library of Science (PLoS)
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Language
English
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Publisher
Public Library of Science (PLoS)
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Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model. We report that the efficiency of primary transmission of prions from Creutzfeldt-Jakob disease patients to a wild rodent species, the bank vole (Clethrionomys glareolus), is comparable to that...
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Full title
Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles
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TN_cdi_doaj_primary_oai_doaj_org_article_545a1b1acbf7493ab3bccb4b17b37ca0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_545a1b1acbf7493ab3bccb4b17b37ca0
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ISSN
1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.0020012
