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HIF1A signaling selectively supports proliferation of breast cancer in the brain

HIF1A signaling selectively supports proliferation of breast cancer in the brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54abe4889e2240aa9d1bd7861d09df2e

HIF1A signaling selectively supports proliferation of breast cancer in the brain

About this item

Full title

HIF1A signaling selectively supports proliferation of breast cancer in the brain

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-12, Vol.11 (1), p.6311-6311, Article 6311

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Blood-borne metastasis to the brain is a major complication of breast cancer, but cellular pathways that enable cancer cells to selectively grow in the brain microenvironment are poorly understood. We find that cultured circulating tumor cells (CTCs), derived from blood samples of women with advanced breast cancer and directly inoculated into the m...

Alternative Titles

Full title

HIF1A signaling selectively supports proliferation of breast cancer in the brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_54abe4889e2240aa9d1bd7861d09df2e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54abe4889e2240aa9d1bd7861d09df2e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-20144-w

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