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An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control...

An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54ebf73015d9478d882dbc5a6522a5e5

An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

About this item

Full title

An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-11, Vol.10 (1), p.5108-15, Article 5108

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mounting evidence suggests that the tumor microenvironment is profoundly immunosuppressive. Thus, mitigating tumor immunosuppression is crucial for inducing sustained antitumor immunity. Whereas previous studies involved intratumoral injection, we report here an inhalable nanoparticle-immunotherapy system targeting pulmonary antigen presenting cell...

Alternative Titles

Full title

An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_54ebf73015d9478d882dbc5a6522a5e5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54ebf73015d9478d882dbc5a6522a5e5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13094-5

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