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STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway

STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_55713eefba5d493d89c7d396451b3eb7

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa) is a major factor contributing to its lethality, although the mechanisms remain poorly understood. PTEN is one of the most frequently deleted genes in mPCa. Here we show a frequent genomic co-deletion of PTEN and STAT3 in liquid biopsies of patients with mPCa....

Alternative Titles

Full title

STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_55713eefba5d493d89c7d396451b3eb7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_55713eefba5d493d89c7d396451b3eb7

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-023-01825-8

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