STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
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Author / Creator
Sveriges lantbruksuniversitet , Pencik, Jan , Philippe, Cecile , Schlederer, Michaela , Atas, Emine , Pecoraro, Matteo , Grund-Gröschke, Sandra , Li, Wen Jess , Tracz, Amanda , Heidegger, Isabel , Lagger, Sabine , Trachtová, Karolína , Oberhuber, Monika , Heitzer, Ellen , Aksoy, Osman , Neubauer, Heidi A , Wingelhofer, Bettina , Orlova, Anna , Witzeneder, Nadine , Dillinger, Thomas , Redl, Elisa , Greiner, Georg , D'Andrea, David , Östman, Johnny R , Tangermann, Simone , Hermanova, Ivana , Schäfer, Georg , Sternberg, Felix , Pohl, Elena E , Sternberg, Christina , Varady, Adam , Horvath, Jaqueline , Stoiber, Dagmar , Malcolm, Tim I , Turner, Suzanne D , Parkes, Eileen E , Hantusch, Brigitte , Egger, Gerda , Rose-John, Stefan , Poli, Valeria , Jain, Suneil , Armstrong, Chris W D , Hoermann, Gregor , Goffin, Vincent , Aberger, Fritz , Moriggl, Richard , Carracedo, Arkaitz , McKinney, Cathal , Kennedy, Richard D , Klocker, Helmut , Speicher, Michael R , Tang, Dean G , Moazzami, Ali A , Heery, David M , Hacker, Marcus and Kenner, Lukas
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa) is a major factor contributing to its lethality, although the mechanisms remain poorly understood. PTEN is one of the most frequently deleted genes in mPCa. Here we show a frequent genomic co-deletion of PTEN and STAT3 in liquid biopsies of patients with mPCa....
Alternative Titles
Full title
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
Authors, Artists and Contributors
Author / Creator
Pencik, Jan
Philippe, Cecile
Schlederer, Michaela
Atas, Emine
Pecoraro, Matteo
Grund-Gröschke, Sandra
Li, Wen Jess
Tracz, Amanda
Heidegger, Isabel
Lagger, Sabine
Trachtová, Karolína
Oberhuber, Monika
Heitzer, Ellen
Aksoy, Osman
Neubauer, Heidi A
Wingelhofer, Bettina
Orlova, Anna
Witzeneder, Nadine
Dillinger, Thomas
Redl, Elisa
Greiner, Georg
D'Andrea, David
Östman, Johnny R
Tangermann, Simone
Hermanova, Ivana
Schäfer, Georg
Sternberg, Felix
Pohl, Elena E
Sternberg, Christina
Varady, Adam
Horvath, Jaqueline
Stoiber, Dagmar
Malcolm, Tim I
Turner, Suzanne D
Parkes, Eileen E
Hantusch, Brigitte
Egger, Gerda
Rose-John, Stefan
Poli, Valeria
Jain, Suneil
Armstrong, Chris W D
Hoermann, Gregor
Goffin, Vincent
Aberger, Fritz
Moriggl, Richard
Carracedo, Arkaitz
McKinney, Cathal
Kennedy, Richard D
Klocker, Helmut
Speicher, Michael R
Tang, Dean G
Moazzami, Ali A
Heery, David M
Hacker, Marcus
Kenner, Lukas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_55713eefba5d493d89c7d396451b3eb7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_55713eefba5d493d89c7d396451b3eb7
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-023-01825-8
