Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophag...
Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophagy
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Dentin sialophosphoprotein (
DSPP
) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells). Disease-causing
DSPP
mutations predominantly fall into two categories: 5’ mutations affecting targeting and trafficking, and 3’ − 1 frameshift mut...
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Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophagy
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TN_cdi_doaj_primary_oai_doaj_org_article_55ab9e745bdb4551b1c1f56ebfdaf75c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_55ab9e745bdb4551b1c1f56ebfdaf75c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-33362-1