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Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophag...

Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophag...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_55ab9e745bdb4551b1c1f56ebfdaf75c

Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophagy

About this item

Full title

Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophagy

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-04, Vol.13 (1), p.6393-6393, Article 6393

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dentin sialophosphoprotein (
DSPP
) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells). Disease-causing
DSPP
mutations predominantly fall into two categories: 5’ mutations affecting targeting and trafficking, and 3’ − 1 frameshift mut...

Alternative Titles

Full title

Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_55ab9e745bdb4551b1c1f56ebfdaf75c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_55ab9e745bdb4551b1c1f56ebfdaf75c

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-33362-1

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