Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Senescent cells, formed in response to physiological and oncogenic stresses, facilitate protection from tumourigenesis and aid in tissue repair. However, accumulation of such cells in tissues contributes to age-related pathologies. Resistance of senescent cells to apoptotic stimuli may contribute to their accumulation, yet the molecular mechanisms...
Alternative Titles
Full title
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
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TN_cdi_doaj_primary_oai_doaj_org_article_560479e5b34747fb9d70b2a5aea7e0c2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_560479e5b34747fb9d70b2a5aea7e0c2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11190
