Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition
Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Parkinson's disease (PD) is a neurodegenerative disorder that is characterized by the presence of proteinaceous alpha-synuclein (α-syn) inclusions (Lewy bodies), markers of neuroinflammation and the progressive loss of nigrostriatal dopamine (DA) neurons. These pathological features can be recapitulated in vivo using the α-syn preformed fibril (PFF...
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Full title
Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition
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TN_cdi_doaj_primary_oai_doaj_org_article_5679db2e702a49868c1ad5fd724f257f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5679db2e702a49868c1ad5fd724f257f
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-024-03108-5
