NPRL2 down‐regulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and au...
NPRL2 down‐regulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and autophagy suppression
About this item
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Author / Creator
Wang, Ya‐Chin , Tsai, Ming‐Chao , Chen, Yaw‐Sen , Hsieh, Pei‐Min , Hung, Chao‐Ming , Lin, Hung‐Yu , Hsu, Yao‐Chun , Yeh, Jen‐Hao , Hsiao, Pojen , Su, Yu‐Cheih , Ma, Ching‐Hou , Lee, Chih‐Yuan , Lin, Chih‐Che , Shu, Chih‐Wen , Li, Yu‐Chan , Tsai, Mei‐Hsing , Lin, James Yu , Peng, Wei‐Hao , Yu, Ming‐Lung and Lin, Chih‐Wen
Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Journal title
Language
English
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Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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Scope and Contents
Contents
Hepatocellular carcinoma (HCC) is a highly invasive malignancy. Recently, GATOR1 (Gap Activity TOward Rags 1) complexes have been shown to play an important role in regulating tumor growth. NPRL2 is a critical component of the GATOR1 complex. Therefore, this study used NPRL2 knockdown to investigate how GATORC1 regulates the prognosis and developme...
Alternative Titles
Full title
NPRL2 down‐regulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and autophagy suppression
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_570acea9db984957a14221e692b0d8b3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_570acea9db984957a14221e692b0d8b3
Other Identifiers
ISSN
2471-254X
E-ISSN
2471-254X
DOI
10.1002/hep4.2019
