Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic ce...
Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic cells for efficient priming of CD8+ T cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Antigen cognate dendritic cell (DC)-T cell synaptic interactions drive activation of T cells and instruct DCs. Upon receiving CD4
+
T cell help, post-synaptic DCs (psDCs) are licensed to generate CD8
+
T cell responses. However, the cellular and molecular mechanisms that enable psDCs licensing remain unclear. Here, we describe that anti...
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Full title
Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic cells for efficient priming of CD8+ T cells
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TN_cdi_doaj_primary_oai_doaj_org_article_575e9711ad8c4a6bab6822f8ba691d6a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_575e9711ad8c4a6bab6822f8ba691d6a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42480-3
