Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity
Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity
About this item
Full title
Author / Creator
Planas-Serra, Laura , Launay, Nathalie , Goicoechea, Leire , Heron, Bénédicte , Jou, Cristina , Juliá-Palacios, Natalia , Ruiz, Montserrat , Fourcade, Stéphane , Casasnovas, Carlos , De La Torre, Carolina , Gelot, Antoinette , Marsal, Maria , Loza-Alvarez, Pablo , García-Cazorla, Àngels , Fatemi, Ali , Ferrer, Isidre , Portero-Otin, Manel , Area-Gómez, Estela and Pujol, Aurora
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Sphingolipids function as membrane constituents and signaling molecules, with crucial roles in human diseases, from neurodevelopmental disorders to cancer, best exemplified in the inborn errors of sphingolipid metabolism in lysosomes. The dihydroceramide desaturase Δ4-dihydroceramide desaturase 1 (DEGS1) acts in the last step of a sector of the sph...
Alternative Titles
Full title
Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity
Authors, Artists and Contributors
Author / Creator
Launay, Nathalie
Goicoechea, Leire
Heron, Bénédicte
Jou, Cristina
Juliá-Palacios, Natalia
Ruiz, Montserrat
Fourcade, Stéphane
Casasnovas, Carlos
De La Torre, Carolina
Gelot, Antoinette
Marsal, Maria
Loza-Alvarez, Pablo
García-Cazorla, Àngels
Fatemi, Ali
Ferrer, Isidre
Portero-Otin, Manel
Area-Gómez, Estela
Pujol, Aurora
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_57a458aa84644ca19559b39fa3a6a489
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_57a458aa84644ca19559b39fa3a6a489
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI162957
