Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disea...
Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. Here we performed an unbiased high-throughput luciferase screening to...
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Full title
Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model
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TN_cdi_doaj_primary_oai_doaj_org_article_57f98ba85a7143c8bb7feb9bb5391a36
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_57f98ba85a7143c8bb7feb9bb5391a36
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-00614-w
