IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmiss...
IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Host factors restricting the transmission of respiratory viruses are poorly characterized. We analyzed the contribution of type I and type III interferon (IFN) using a mouse model in which the virus is selectively administered to the upper airways, mimicking a natural respiratory virus infection. Mice lacking functional IFN-λ receptors (Ifnlr1−/−)...
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Full title
IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission
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TN_cdi_doaj_primary_oai_doaj_org_article_582c927dc0c04f1d916a7f6746b4ac4d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_582c927dc0c04f1d916a7f6746b4ac4d
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.33354
