Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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IRE1α is constitutively active in several cancers and can contribute to cancer progression. Activated IRE1α cleaves
XBP1
mRNA, a key step in production of the transcription factor XBP1s. In addition, IRE1α cleaves select mRNAs through regulated IRE1α-dependent decay (RIDD). Accumulating evidence implicates IRE1α in the regulation of lipid met...
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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_5880a9d0a80d435dbe79e1dfb4bc9b6f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5880a9d0a80d435dbe79e1dfb4bc9b6f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30159-0