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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5880a9d0a80d435dbe79e1dfb4bc9b6f

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

About this item

Full title

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-05, Vol.13 (1), p.2493-2493, Article 2493

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

IRE1α is constitutively active in several cancers and can contribute to cancer progression. Activated IRE1α cleaves
XBP1
mRNA, a key step in production of the transcription factor XBP1s. In addition, IRE1α cleaves select mRNAs through regulated IRE1α-dependent decay (RIDD). Accumulating evidence implicates IRE1α in the regulation of lipid met...

Alternative Titles

Full title

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5880a9d0a80d435dbe79e1dfb4bc9b6f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5880a9d0a80d435dbe79e1dfb4bc9b6f

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-30159-0

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