Research Advance of TRAIL Molecular Target in the Therapy of Lung Cancer.
Research Advance of TRAIL Molecular Target in the Therapy of Lung Cancer.
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Full title
Author / Creator
Liu, Qian , Ma, Lingdi and Wang, Yong
Publisher
China: Chinese Anti-Cancer Association Chinese Antituberculosis Association
Journal title
Language
Chinese
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Publisher
China: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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Contents
目前肺癌的发病率在全球范围内呈持续上升的趋势。在中国，肺癌的发病率和死亡率在所有肿瘤中是最高的。肺癌患者中，只有30%的非小细胞肺癌可以通过外科手术切除，但手术后5年存活率很低，生活质量也不高，晚期不能手术的患者通常只能采用常规化疗或放疗，毒副作用大，疗效不理想。因此，寻找新的肺癌治疗手段是目前亟待解决的难题。肿瘤坏死因子相关凋亡诱导配体（tumor necrosis factor-related apoptosis-inducing ligand，TRAIL）是近年发现的肿瘤坏死因子（tumor necrosis factor，TNF）家族成员，与死亡受体结合后可特异性地诱导肿瘤细胞和恶性转化细胞凋亡，对正常组织细胞无作用，故以TRAIL为靶点的分子治疗已成为肿瘤治疗研究的新热点。 1 T...
Alternative Titles
Full title
Research Advance of TRAIL Molecular Target in the Therapy of Lung Cancer.
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_589ac8e9967a414198ab32ddec335e08
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_589ac8e9967a414198ab32ddec335e08
Other Identifiers
ISSN
1009-3419
E-ISSN
1999-6187
DOI
10.3779/j.issn.1009-3419.2009.03.015
