Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-d...
Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft
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Author / Creator
Landuzzi, Lorena , Palladini, Arianna , Ceccarelli, Claudio , Asioli, Sofia , Nicoletti, Giordano , Giusti, Veronica , Ruzzi, Francesca , Ianzano, Marianna L. , Scalambra, Laura , Laranga, Roberta , Balboni, Tania , Arigoni, Maddalena , Olivero, Martina , Calogero, Raffaele A. , De Giovanni, Carla , Dall’Ora, Massimiliano , Di Oto, Enrico , Santini, Donatella , Foschini, Maria Pia , Cucchi, Maria Cristina , Zanotti, Simone , Taffurelli, Mario , Nanni, Patrizia and Lollini, Pier-Luigi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
We established patient-derived xenografts (PDX) from human primary breast cancers and studied whether stability or progressive events occurred during long-term in vivo passages (up to 4 years) in severely immunodeficient mice. While most PDX showed stable biomarker expression and growth phenotype, a HER2-positive PDX (PDX-BRB4) originated a subline...
Alternative Titles
Full title
Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft
Authors, Artists and Contributors
Author / Creator
Palladini, Arianna
Ceccarelli, Claudio
Asioli, Sofia
Nicoletti, Giordano
Giusti, Veronica
Ruzzi, Francesca
Ianzano, Marianna L.
Scalambra, Laura
Laranga, Roberta
Balboni, Tania
Arigoni, Maddalena
Olivero, Martina
Calogero, Raffaele A.
De Giovanni, Carla
Dall’Ora, Massimiliano
Di Oto, Enrico
Santini, Donatella
Foschini, Maria Pia
Cucchi, Maria Cristina
Zanotti, Simone
Taffurelli, Mario
Nanni, Patrizia
Lollini, Pier-Luigi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_59a0895a37d34757859e7e9b853a7ad6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59a0895a37d34757859e7e9b853a7ad6
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-81085-y
