Reactivated endogenous retroviruses promote protein aggregate spreading
Reactivated endogenous retroviruses promote protein aggregate spreading
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Prion-like spreading of protein misfolding is a characteristic of neurodegenerative diseases, but the exact mechanisms of intercellular protein aggregate dissemination remain unresolved. Evidence accumulates that endogenous retroviruses, remnants of viral germline infections that are normally epigenetically silenced, become upregulated in neurodege...
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Reactivated endogenous retroviruses promote protein aggregate spreading
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TN_cdi_doaj_primary_oai_doaj_org_article_59bc77799ee240d9b3249e422cd48dea
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59bc77799ee240d9b3249e422cd48dea
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-40632-z