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Molecular architecture of the mammalian 2-oxoglutarate dehydrogenase complex

Molecular architecture of the mammalian 2-oxoglutarate dehydrogenase complex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59d9da64dee0427ca074ee195af4d958

Molecular architecture of the mammalian 2-oxoglutarate dehydrogenase complex

About this item

Full title

Molecular architecture of the mammalian 2-oxoglutarate dehydrogenase complex

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-09, Vol.15 (1), p.8407-15, Article 8407

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The 2-oxoglutarate dehydrogenase complex (OGDHc) orchestrates a critical reaction regulating the TCA cycle. Although the structure of each OGDHc subunit has been solved, the architecture of the intact complex and inter-subunit interactions still remain unknown. Here we report the assembly of native, intact OGDHc from
Sus scrofa
heart tissue u...

Alternative Titles

Full title

Molecular architecture of the mammalian 2-oxoglutarate dehydrogenase complex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_59d9da64dee0427ca074ee195af4d958

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59d9da64dee0427ca074ee195af4d958

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-52792-7

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