Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain exp...
Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects
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Author / Creator
23andMe Research Team , Krohn, Lynne , Heilbron, Karl , Blauwendraat, Cornelis , Reynolds, Regina H. , Yu, Eric , Senkevich, Konstantin , Rudakou, Uladzislau , Estiar, Mehrdad A. , Gustavsson, Emil K. , Brolin, Kajsa , Ruskey, Jennifer A. , Freeman, Kathryn , Asayesh, Farnaz , Chia, Ruth , Arnulf, Isabelle , Hu, Michele T. M. , Montplaisir, Jacques Y. , Gagnon, Jean-François , Desautels, Alex , Dauvilliers, Yves , Gigli, Gian Luigi , Valente, Mariarosaria , Janes, Francesco , Bernardini, Andrea , Högl, Birgit , Stefani, Ambra , Ibrahim, Abubaker , Šonka, Karel , Kemlink, David , Oertel, Wolfgang , Janzen, Annette , Plazzi, Giuseppe , Biscarini, Francesco , Antelmi, Elena , Figorilli, Michela , Puligheddu, Monica , Mollenhauer, Brit , Trenkwalder, Claudia , Sixel-Döring, Friederike , Cochen De Cock, Valérie , Monaca, Christelle Charley , Heidbreder, Anna , Ferini-Strambi, Luigi , Dijkstra, Femke , Viaene, Mineke , Abril, Beatriz , Boeve, Bradley F. , Scholz, Sonja W. , Ryten, Mina , Bandres-Ciga, Sara , Noyce, Alastair , Cannon, Paul , Pihlstrøm, Lasse , Nalls, Mike A. , Singleton, Andrew B. , Rouleau, Guy A. , Postuma, Ronald B. and Gan-Or, Ziv
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Rapid-eye movement (REM) sleep behavior disorder (RBD), enactment of dreams during REM sleep, is an early clinical symptom of alpha-synucleinopathies and defines a more severe subtype. The genetic background of RBD and its underlying mechanisms are not well understood. Here, we perform a genome-wide association study of RBD, identifying five RBD ri...
Alternative Titles
Full title
Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects
Authors, Artists and Contributors
Author / Creator
Krohn, Lynne
Heilbron, Karl
Blauwendraat, Cornelis
Reynolds, Regina H.
Yu, Eric
Senkevich, Konstantin
Rudakou, Uladzislau
Estiar, Mehrdad A.
Gustavsson, Emil K.
Brolin, Kajsa
Ruskey, Jennifer A.
Freeman, Kathryn
Asayesh, Farnaz
Chia, Ruth
Arnulf, Isabelle
Hu, Michele T. M.
Montplaisir, Jacques Y.
Gagnon, Jean-François
Desautels, Alex
Dauvilliers, Yves
Gigli, Gian Luigi
Valente, Mariarosaria
Janes, Francesco
Bernardini, Andrea
Högl, Birgit
Stefani, Ambra
Ibrahim, Abubaker
Šonka, Karel
Kemlink, David
Oertel, Wolfgang
Janzen, Annette
Plazzi, Giuseppe
Biscarini, Francesco
Antelmi, Elena
Figorilli, Michela
Puligheddu, Monica
Mollenhauer, Brit
Trenkwalder, Claudia
Sixel-Döring, Friederike
Cochen De Cock, Valérie
Monaca, Christelle Charley
Heidbreder, Anna
Ferini-Strambi, Luigi
Dijkstra, Femke
Viaene, Mineke
Abril, Beatriz
Boeve, Bradley F.
Scholz, Sonja W.
Ryten, Mina
Bandres-Ciga, Sara
Noyce, Alastair
Cannon, Paul
Pihlstrøm, Lasse
Nalls, Mike A.
Singleton, Andrew B.
Rouleau, Guy A.
Postuma, Ronald B.
Gan-Or, Ziv
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_59eca1d6c47b4c98aed465f4c7a60228
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_59eca1d6c47b4c98aed465f4c7a60228
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-34732-5
