GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type...
GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
About this item
Full title
Author / Creator
Fernandez, 3rd, Rafael Jesus , Gardner, Zachary J G , Slovik, Katherine J , Liberti, Derek C , Estep, Katrina N , Yang, Wenli , Chen, Qijun , Santini, Garrett T , Perez, Javier V , Root, Sarah , Bhatia, Ranvir , Tobias, John W , Babu, Apoorva , Morley, Michael P , Frank, David B , Morrisey, Edward E , Lengner, Christopher J and Johnson, F Brad
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Dyskeratosis congenita (DC) is a rare genetic disorder characterized by deficiencies in telomere maintenance leading to very short telomeres and the premature onset of certain age-related diseases, including pulmonary fibrosis (PF). PF is thought to derive from epithelial failure, particularly that of type II alveolar epithelial (AT2) cells, which...
Alternative Titles
Full title
GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
Authors, Artists and Contributors
Author / Creator
Gardner, Zachary J G
Slovik, Katherine J
Liberti, Derek C
Estep, Katrina N
Yang, Wenli
Chen, Qijun
Santini, Garrett T
Perez, Javier V
Root, Sarah
Bhatia, Ranvir
Tobias, John W
Babu, Apoorva
Morley, Michael P
Frank, David B
Morrisey, Edward E
Lengner, Christopher J
Johnson, F Brad
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5a2e0adc44d4496d8818d07ddfebb226
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a2e0adc44d4496d8818d07ddfebb226
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.64430
