Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
About this item
Full title
Author / Creator
Ho, Jemima , Yang, Xuexin , Nikou, Spyridoula-Angeliki , Kichik, Nessim , Donkin, Andrew , Ponde, Nicole O. , Richardson, Jonathan P. , Gratacap, Remi L. , Archambault, Linda S. , Zwirner, Christian P. , Murciano, Celia , Henley-Smith, Rhonda , Thavaraj, Selvam , Tynan, Christopher J. , Gaffen, Sarah L. , Hube, Bernhard , Wheeler, Robert T. , Moyes, David L. and Naglik, Julian R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Candida albicans
is a fungal pathobiont, able to cause epithelial cell damage and immune activation. These functions have been attributed to its secreted toxin, candidalysin, though the molecular mechanisms are poorly understood. Here, we identify epidermal growth factor receptor (EGFR) as a critical component of candidalysin-triggered immune re...
Alternative Titles
Full title
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
Authors, Artists and Contributors
Author / Creator
Yang, Xuexin
Nikou, Spyridoula-Angeliki
Kichik, Nessim
Donkin, Andrew
Ponde, Nicole O.
Richardson, Jonathan P.
Gratacap, Remi L.
Archambault, Linda S.
Zwirner, Christian P.
Murciano, Celia
Henley-Smith, Rhonda
Thavaraj, Selvam
Tynan, Christopher J.
Gaffen, Sarah L.
Hube, Bernhard
Wheeler, Robert T.
Moyes, David L.
Naglik, Julian R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5a35ef4f63da4f5da3fd3d4b2fc4fa96
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a35ef4f63da4f5da3fd3d4b2fc4fa96
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09915-2
