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ArticlesPeer ReviewedFull Text
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
Author / Creator:Kasper, Lydia ; König, Annika ; Koenig, Paul-Albert ; Gresnigt, Mark S. ; Westman, Johannes ; Drummond, Rebecca A. ; Lionakis, Michail S. ; Groß, Olaf ; Ruland, Jürgen ; Naglik, Julian R. ; Hube, Bernhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4260-20, Article 4260
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Candidalysin is a fungal peptide toxin critical for mucosal infection
Author / Creator:Moyes, David L. ; Wilson, Duncan ; Richardson, Jonathan P. ; Mogavero, Selene ; Tang, Shirley X. ; Wernecke, Julia ; Höfs, Sarah ; Gratacap, Remi L. ; Robbins, Jon ; Runglall, Manohursingh ; Murciano, Celia ; Blagojevic, Mariana ; Thavaraj, Selvam ; Förster, Toni M. ; Hebecker, Betty ; Kasper, Lydia ; Vizcay, Gema ; Iancu, Simona I. ; Kichik, Nessim ; Häder, Antje ; Kurzai, Oliver ; Luo, Ting ; Krüger, Thomas ; Kniemeyer, Olaf ; Cota, Ernesto ; Bader, Oliver ; Wheeler, Robert T. ; Gutsmann, Thomas ; Hube, Bernhard ; Naglik, Julian R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-04, Vol.532 (7597), p.64-68
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Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
Author / Creator:Ho, Jemima ; Yang, Xuexin ; Nikou, Spyridoula-Angeliki ; Kichik, Nessim ; Donkin, Andrew ; Ponde, Nicole O. ; Richardson, Jonathan P. ; Gratacap, Remi L. ; Archambault, Linda S. ; Zwirner, Christian P. ; Murciano, Celia ; Henley-Smith, Rhonda ; Thavaraj, Selvam ; Tynan, Christopher J. ; Gaffen, Sarah L. ; Hube, Bernhard ; Wheeler, Robert T. ; Moyes, David L. ; Naglik, Julian R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-05, Vol.10 (1), p.2297-2297, Article 2297
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A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis
Author / Creator:Liu, Junyan ; Willems, Hubertine M E ; Sansevere, Emily A ; Allert, Stefanie ; Barker, Katherine S ; Lowes, David J ; Dixson, Andrew C ; Xu, Zhenbo ; Miao, Jian ; DeJarnette, Christian ; Tournu, Helene ; Palmer, Glen E ; Richardson, Jonathan P ; Barrera, Francisco N ; Hube, Bernhard ; Naglik, Julian R ; Peters, Brian M
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2021-09, Vol.17 (9), p.e1009884
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Candida albicans pathogenicity and epithelial immunity
Author / Creator:Naglik, Julian R ; Richardson, Jonathan P ; Moyes, David L
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2014-08, Vol.10 (8), p.e1004257-e1004257
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Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells
Author / Creator:Moyes, David L ; Murciano, Celia ; Runglall, Manohursingh ; Islam, Ayesha ; Thavaraj, Selvam ; Naglik, Julian R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-11, Vol.6 (11), p.e26580-e26580
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ArticlesPeer ReviewedFull Text
Some like it hot: Candida activation of inflammasomes
Author / Creator:Camilli, Giorgio ; Griffiths, James S ; Ho, Jemima ; Richardson, Jonathan P ; Naglik, Julian R
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-10, Vol.16 (10), p.e1008975-e1008975
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Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB-mediated barrier protection
Author / Creator:Sprague, Jakob L ; Schille, Tim B ; Allert, Stefanie ; Trümper, Verena ; Lier, Adrian ; Großmann, Peter ; Priest, Emily L ; Tsavou, Antzela ; Panagiotou, Gianni ; Naglik, Julian R ; Wilson, Duncan ; Schäuble, Sascha ; Kasper, Lydia ; Hube, Bernhard
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-03, Vol.20 (3), p.e1012031-e1012031
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ArticlesPeer ReviewedFull Text
Candida-Epithelial Interactions
Author / Creator:Richardson, Jonathan P ; Ho, Jemima ; Naglik, Julian R
Publisher:Switzerland: MDPI AG
Journal title:Journal of fungi (Basel), 2018-02, Vol.4 (1), p.22
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ArticlesPeer ReviewedFull Text
The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage
Author / Creator:Wilson, Duncan ; Naglik, Julian R ; Hube, Bernhard
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-10, Vol.12 (10), p.e1005867-e1005867
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ArticlesPeer ReviewedFull Text
Evaluation of the role of Candida albicans agglutinin-like sequence (Als) proteins in human oral epithelial cell interactions
Author / Creator:Murciano, Celia ; Moyes, David L ; Runglall, Manohursingh ; Tobouti, Priscila ; Islam, Ayesha ; Hoyer, Lois L ; Naglik, Julian R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e33362-e33362
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Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells
Author / Creator:Ho, Jemima ; Wickramasinghe, Don N ; Nikou, Spyridoula-Angeliki ; Hube, Bernhard ; Richardson, Jonathan P ; Naglik, Julian R
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.699
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ArticlesPeer ReviewedFull Text
Candida albicans Interactions with Mucosal Surfaces during Health and Disease
Author / Creator:Nikou, Spyridoula-Angeliki ; Kichik, Nessim ; Brown, Rhys ; Ponde, Nicole O ; Ho, Jemima ; Naglik, Julian R ; Richardson, Jonathan P
Publisher:Switzerland: MDPI AG
Journal title:Pathogens (Basel), 2019-04, Vol.8 (2), p.53
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ArticlesPeer ReviewedFull Text
Correction: Oral and Vaginal Epithelial Cell Lines Bind and Transfer Cell-Free Infectious HIV-1 to Permissive Cells but Are Not Productively Infected
Author / Creator:Kohli, Arinder ; Islam, Ayesha ; Moyes, David L ; Murciano, Celia ; Shen, Chengguo ; Challacombe, Stephen J ; Naglik, Julian R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-02, Vol.15 (2), p.e0229553-e0229553
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ArticlesPeer ReviewedFull Text
Oral and vaginal epithelial cell lines bind and transfer cell-free infectious HIV-1 to permissive cells but are not productively infected
Author / Creator:Kohli, Arinder ; Islam, Ayesha ; Moyes, David L ; Murciano, Celia ; Shen, Chengguo ; Challacombe, Stephen J ; Naglik, Julian R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-05, Vol.9 (5), p.e98077-e98077
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Cell cycle-independent phospho-regulation of Fkh2 during hyphal growth regulates Candida albicans pathogenesis
Author / Creator:Greig, Jamie A ; Sudbery, Ian M ; Richardson, Jonathan P ; Naglik, Julian R ; Wang, Yue ; Sudbery, Peter E
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2015-01, Vol.11 (1), p.e1004630-e1004630
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Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells
Author / Creator:Wagener, Jeanette ; Weindl, Günther ; de Groot, Piet W J ; de Boer, Albert D ; Kaesler, Susanne ; Thavaraj, Selvam ; Bader, Oliver ; Mailänder-Sanchez, Daniela ; Borelli, Claudia ; Weig, Michael ; Biedermann, Tilo ; Naglik, Julian R ; Korting, Hans Christian ; Schaller, Martin
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e50518-e50518
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ArticlesPeer ReviewedFull Text
Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia
Author / Creator:Schaller, Martin ; Zakikhany, Katherina ; Naglik, Julian R ; Weindl, Günther ; Hube, Bernhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2006-12, Vol.1 (6), p.2767-2773
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Special Issue: Mucosal Fungal Infections
Author / Creator:Richardson, Jonathan P ; Naglik, Julian R
Publisher:Switzerland: MDPI
Journal title:Journal of fungi (Basel), 2018-03, Vol.4 (2), p.43
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Immune regulation by fungal strain diversity in inflammatory bowel disease
Author / Creator:Li, Xin V. ; Leonardi, Irina ; Putzel, Gregory G. ; Semon, Alexa ; Fiers, William D. ; Kusakabe, Takato ; Lin, Woan-Yu ; Gao, Iris H. ; Doron, Itai ; Gutierrez-Guerrero, Alejandra ; DeCelie, Meghan B. ; Carriche, Guilhermina M. ; Mesko, Marissa ; Yang, Chen ; Naglik, Julian R. ; Hube, Bernhard ; Scherl, Ellen J. ; Iliev, Iliyan D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-03, Vol.603 (7902), p.672-678
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Showing 1 to 20 of 46 results

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The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

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Candidalysin is a fungal peptide toxin critical for mucosal infection

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Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

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A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis

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Candida albicans pathogenicity and epithelial immunity

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Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells

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Some like it hot: Candida activation of inflammasomes

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Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB-mediated barrier protection

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Candida-Epithelial Interactions

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The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage

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Evaluation of the role of Candida albicans agglutinin-like sequence (Als) proteins in human oral epithelial cell interactions

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Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells

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Candida albicans Interactions with Mucosal Surfaces during Health and Disease

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Correction: Oral and Vaginal Epithelial Cell Lines Bind and Transfer Cell-Free Infectious HIV-1 to Permissive Cells but Are Not Productively Infected

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Oral and vaginal epithelial cell lines bind and transfer cell-free infectious HIV-1 to permissive cells but are not productively infected

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Cell cycle-independent phospho-regulation of Fkh2 during hyphal growth regulates Candida albicans pathogenesis

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Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells

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Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia

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Special Issue: Mucosal Fungal Infections

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Immune regulation by fungal strain diversity in inflammatory bowel disease

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