Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic tra...
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy
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Publisher
England: eLife Sciences Publications, Ltd
Journal title
Language
English
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Publisher
England: eLife Sciences Publications, Ltd
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Contents
Abundant filamentous inclusions of tau are characteristic of more than 20 neurodegenerative diseases that are collectively termed tauopathies. Electron cryo-microscopy (cryo-EM) structures of tau amyloid filaments from human brain revealed that distinct tau folds characterise many different diseases. A lack of laboratory-based model systems to gene...
Alternative Titles
Full title
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_5a43a79ce71b4064afeb8da1c61ff062
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a43a79ce71b4064afeb8da1c61ff062
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.76494
