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RIPK1 protects hepatocytes from death in Fas-induced hepatitis

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a69f5dded0846c29b4a7635d8cd5204

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

About this item

Full title

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.9205-10, Article 9205

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatocyte death is a central event during liver disease progression, in which immune cells play key roles by activating members of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF), including TNFR1 (TNFRSF1A), Fas (TNFRSF6) and TRAIL-R2 (TNFRSF10B). Receptor Interacting Protein Kinase 1 (RIPK1) emerged as a signaling node downstream of these...

Alternative Titles

Full title

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5a69f5dded0846c29b4a7635d8cd5204

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a69f5dded0846c29b4a7635d8cd5204

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-09789-8

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