APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alz...
APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases
About this item
Full title
Author / Creator
Perez-Corredor, Paula , Vanderleest, Timothy E , Vacano, Guido N , Sanchez, Justin S , Villalba-Moreno, Nelson D , Marino, Claudia , Krasemann, Susanne , Mendivil-Perez, Miguel A , Aguillón, David , Jiménez-Del-Río, Marlene , Baena, Ana , Sepulveda-Falla, Diego , Lopera, Francisco , Quiroz, Yakeel T , Arboleda-Velasquez, Joseph F and Mazzarino, Randall C
Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: Frontiers Research Foundation
Subjects
More information
Scope and Contents
Contents
A patient with the
E280A mutation and homozygous for
Christchurch (
) displayed extreme resistance to Alzheimer's disease (AD) cognitive decline and tauopathy, despite having a high amyloid burden. To further investigate the differences in biological processes attributed to
, we generated induced pluripotent stem (iPS) cell-derived cere...
Alternative Titles
Full title
APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases
Authors, Artists and Contributors
Author / Creator
Vanderleest, Timothy E
Vacano, Guido N
Sanchez, Justin S
Villalba-Moreno, Nelson D
Marino, Claudia
Krasemann, Susanne
Mendivil-Perez, Miguel A
Aguillón, David
Jiménez-Del-Río, Marlene
Baena, Ana
Sepulveda-Falla, Diego
Lopera, Francisco
Quiroz, Yakeel T
Arboleda-Velasquez, Joseph F
Mazzarino, Randall C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5a75deb4bb57460d9fea9624ee74d0f7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5a75deb4bb57460d9fea9624ee74d0f7
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2024.1373568
