Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
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Author / Creator
Yee, Patricia P. , Wei, Yiju , Kim, Soo-Yeon , Lu, Tong , Chih, Stephen Y. , Lawson, Cynthia , Tang, Miaolu , Liu, Zhijun , Anderson, Benjamin , Thamburaj, Krishnamoorthy , Young, Megan M. , Aregawi, Dawit G. , Glantz, Michael J. , Zacharia, Brad E. , Specht, Charles S. , Wang, Hong-Gang and Li, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tumor necrosis commonly exists and predicts poor prognoses in many cancers. Although it is thought to result from chronic ischemia, the underlying nature and mechanisms driving the involved cell death remain obscure. Here, we show that necrosis in glioblastoma (GBM) involves neutrophil-triggered ferroptosis. In a hyperactivated transcriptional coac...
Alternative Titles
Full title
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
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TN_cdi_doaj_primary_oai_doaj_org_article_5aa48c67defa41babccc7a4dbd4c5fc0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5aa48c67defa41babccc7a4dbd4c5fc0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19193-y
