Modeling unveils sex differences of signaling networks in mouse embryonic stem cells
Modeling unveils sex differences of signaling networks in mouse embryonic stem cells
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London: EMBO Press
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Language
English
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London: EMBO Press
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For a short period during early development of mammalian embryos, both X chromosomes in females are active, before dosage compensation is ensured through X-chromosome inactivation. In female mouse embryonic stem cells (mESCs), which carry two active X chromosomes, increased X-dosage affects cell signaling and impairs differentiation. The underlying...
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Full title
Modeling unveils sex differences of signaling networks in mouse embryonic stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_5b44e3745a824717b6b7764ab828cf7a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b44e3745a824717b6b7764ab828cf7a
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.202211510
