Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia
Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia
About this item
Full title
Author / Creator
Andreu-Bernabeu, Álvaro , Díaz-Caneja, Covadonga M. , Costas, Javier , De Hoyos, Lucía , Stella, Carol , Gurriarán, Xaquín , Alloza, Clara , Fañanás, Lourdes , Bobes, Julio , González-Pinto, Ana , Crespo-Facorro, Benedicto , Martorell, Lourdes , Vilella, Elisabet , Muntané, Gerard , Nacher, Juan , Molto, María Dolores , Aguilar, Eduardo Jesús , Parellada, Mara , Arango, Celso and González-Peñas, Javier
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Previous research suggests an association of loneliness and social isolation (LNL-ISO) with schizophrenia. Here, we demonstrate a LNL-ISO polygenic score contribution to schizophrenia risk in an independent case-control sample (N = 3,488). We then subset schizophrenia predisposing variation based on its effect on LNL-ISO. We find that genetic varia...
Alternative Titles
Full title
Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia
Authors, Artists and Contributors
Author / Creator
Díaz-Caneja, Covadonga M.
Costas, Javier
De Hoyos, Lucía
Stella, Carol
Gurriarán, Xaquín
Alloza, Clara
Fañanás, Lourdes
Bobes, Julio
González-Pinto, Ana
Crespo-Facorro, Benedicto
Martorell, Lourdes
Vilella, Elisabet
Muntané, Gerard
Nacher, Juan
Molto, María Dolores
Aguilar, Eduardo Jesús
Parellada, Mara
Arango, Celso
González-Peñas, Javier
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5b795e889cbd4e118fc051b5eba3c568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5b795e889cbd4e118fc051b5eba3c568
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27598-6
