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Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote br...

Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote br...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5bbfe85ec77442b28df66c2ab5a22262

Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion

About this item

Full title

Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion

Publisher

Melbourne: John Wiley & Sons Australia, Ltd

Journal title

Thoracic cancer, 2023-06, Vol.14 (16), p.1477-1491

Language

English

Formats

Publication information

Publisher

Melbourne: John Wiley & Sons Australia, Ltd

More information

Scope and Contents

Contents

Background
Emerging evidence has revealed that tumor‐associated macrophages (TAMs) and exosomes play a crucial role in the microenvironment for tumor growth. However, the mechanisms through which exosomal miRNAs modulate TAMs and tumor development in breast cancer are not fully understood.
Methods
We constructed a macrophage model and an i...

Alternative Titles

Full title

Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5bbfe85ec77442b28df66c2ab5a22262

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5bbfe85ec77442b28df66c2ab5a22262

Other Identifiers

ISSN

1759-7706,1759-7714

E-ISSN

1759-7714

DOI

10.1111/1759-7714.14891

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