Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote br...
Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion
About this item
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Author / Creator
Publisher
Melbourne: John Wiley & Sons Australia, Ltd
Journal title
Language
English
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Publisher
Melbourne: John Wiley & Sons Australia, Ltd
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Contents
Background
Emerging evidence has revealed that tumor‐associated macrophages (TAMs) and exosomes play a crucial role in the microenvironment for tumor growth. However, the mechanisms through which exosomal miRNAs modulate TAMs and tumor development in breast cancer are not fully understood.
Methods
We constructed a macrophage model and an i...
Alternative Titles
Full title
Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion
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TN_cdi_doaj_primary_oai_doaj_org_article_5bbfe85ec77442b28df66c2ab5a22262
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5bbfe85ec77442b28df66c2ab5a22262
Other Identifiers
ISSN
1759-7706,1759-7714
E-ISSN
1759-7714
DOI
10.1111/1759-7714.14891