Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generat...
Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung
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Author / Creator
Miura, Akihiro , Sarmah, Hemanta , Tanaka, Junichi , Hwang, Youngmin , Sawada, Anri , Shimamura, Yuko , Otoshi, Takehiro , Kondo, Yuri , Fang, Yinshan , Shimizu, Dai , Ninish, Zurab , Suer, Jake Le , Dubois, Nicole C , Davis, Jennifer , Toyooka, Shinichi , Wu, Jun , Que, Jianwen , Hawkins, Finn J , Lin, Chyuan-Sheng and Mori, Munemasa
Publisher
England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Contents
Millions suffer from incurable lung diseases, and the donor lung shortage hampers organ transplants. Generating the whole organ in conjunction with the thymus is a significant milestone for organ transplantation because the thymus is the central organ to educate immune cells. Using lineage-tracing mice and human pluripotent stem cell (PSC)-derived...
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Full title
Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung
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TN_cdi_doaj_primary_oai_doaj_org_article_5cf0469dedb0467cb9d40502533f7091
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5cf0469dedb0467cb9d40502533f7091
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.86105
