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Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d0891152a3a43dc8053bfd08538105d

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

About this item

Full title

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2019-06, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

The hantavirus envelope glycoproteins Gn and Gc mediate virion assembly and cell entry, with Gc driving fusion of viral and endosomal membranes. Although the X-ray structures and overall arrangement of Gn and Gc on the hantavirus spikes are known, their detailed interactions are not. Here we show that the lateral contacts between spikes are mediate...

Alternative Titles

Full title

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5d0891152a3a43dc8053bfd08538105d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d0891152a3a43dc8053bfd08538105d

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.46028

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